Suppositories
Okinazole L100
オキナゾールL100

For recurrent vaginal candidiasis only, after previous diagnosis and treatment by a doctor.
Active ingredient per tablet: Oxiconazole nitrate 100 mg. Pack: 6 vaginal tablets.
Ages 15 to 59. Do not use under 15 or at 60 and over.
- Do not use if pregnant or possibly pregnant. Consult a pharmacist and read the complete insert before use.
- One tablet daily for 6 consecutive days. Do not use during menstruation.
- See a doctor if symptoms do not improve after 3 days or have not disappeared after 6 days.
Directions & precautions
Inactive ingredients: Lactose hydrate, crystalline cellulose, hydroxypropyl cellulose, citric acid hydrate, magnesium stearate.
Directions: Insert one tablet deep into the vagina once daily, preferably at bedtime, for 6 consecutive days. Continue for all 6 days even if symptoms disappear earlier. Stop and see a doctor if symptoms do not improve after 3 days or have not disappeared after 6 days.
Wash your hands, remove the tablet from its blister, and insert it with a finger. Do not use an applicator. Wash your hands afterward. For vaginal use only; if swallowed, see a doctor immediately.
Do not use during menstruation. If your period starts during treatment, stop and see a doctor.
Do not use if:
- You have never had vaginal candidiasis diagnosed and treated by a doctor, or are unsure whether symptoms are a recurrence.
- You have had a recurrence within 2 months, or two or more episodes within 6 months.
- You have fever, chills, nausea, vomiting, lower abdominal pain, back or shoulder pain, irregular or abnormal bleeding, bloody discharge, vaginal or vulval ulcers, blisters or pain, or painful or difficult urination.
- You have been diagnosed with diabetes, take anticoagulants such as warfarin, have had an allergic reaction to this medicine or its ingredients, or are pregnant or may be pregnant.
During treatment, do not apply other skin medicines to the vulva unless they are candidiasis treatments.
Consult a doctor or pharmacist before use if you are receiving medical treatment, breastfeeding, or have had allergic reactions to medicines or other substances.
Possible side effects: Vaginal throbbing pain, swelling, redness, irritation, itching or a feeling of heat. Stop immediately and consult a doctor or pharmacist with the package insert if these occur.
During treatment: Avoid sexual intercourse, spermicides and washing inside the vagina. Follow the insert's hygiene precautions. White lumps or paste-like material may be discharged as the tablet leaves the body.
Storage: Keep in a cool, dry place away from direct sunlight and out of children's reach. Keep in the original container and do not use after the expiry date.
Source: Japanese package insert (PDF) · Manufacturer product page.
English summary translated from the currently linked Japanese insert; checked September 29, 2026. Read the complete insert before use.
Meditreat (vaginal suppositories)
メディトリート

For recurrent vaginal candidiasis only, after previous diagnosis and treatment by a doctor.
Active ingredient per suppository: Miconazole nitrate 100 mg.
Ages 15 to 59. Do not use under 15 or at 60 and over.
- Do not use if pregnant or possibly pregnant. Consult a pharmacist and read the complete insert before use.
- One suppository daily at bedtime for 6 consecutive days. Avoid use during menstruation.
- See a doctor if symptoms do not improve after 3 days or have not disappeared after 6 days.
Directions & precautions
Inactive ingredient: Hard fat.
Directions: Insert one suppository deep into the vagina once daily at bedtime for 6 consecutive days. Continue for all 6 days even if symptoms disappear earlier. See a doctor if symptoms do not improve after 3 days or have not disappeared after 6 days.
Before use, bathe or clean the affected area with lukewarm water. Wash your hands before and after use. Remove the suppository from its wrapper before insertion. Do not use an applicator. Use only inside the vagina.
If the suppository is too soft, cool it briefly before use. If too hard, allow it to soften before use. Avoid use during menstruation; if your period starts during treatment, stop and see a doctor.
Do not use if:
- This may be your first episode, you have not previously received a doctor's diagnosis and treatment, or you are unsure whether symptoms are a recurrence.
- You have had an allergic reaction to this medicine or its ingredients, or are pregnant or may be pregnant.
- You have fever, chills, lower abdominal pain, back or shoulder pain, colored or blood-stained discharge, fishy-smelling discharge, missed periods, irregular or abnormal vaginal bleeding, or vaginal or vulval ulcers, swelling or sores.
- You have been diagnosed with diabetes or take anticoagulants such as warfarin.
- Episodes recur every 1 to 2 months, or you have had two or more episodes within 6 months.
During treatment, do not apply other skin medicines to the vulva unless they are candidiasis treatments.
Consult a doctor or pharmacist before use if you are receiving medical treatment, have had allergic reactions to medicines or other substances, or are breastfeeding.
Possible side effects: If hives or itching occur outside the vagina after use, stop immediately and consult a doctor or pharmacist with the package insert. Vaginal itching, redness, pain, a feeling of heat or irritation may also occur; if these persist or worsen, stop and consult a doctor or pharmacist with the insert.
Latex precautions: Avoid contact with latex contraceptives such as condoms or diaphragms, as the medicine may damage them.
Storage: Keep at or below 30°C in a cool, dry place away from direct sunlight and out of children's reach. Refrigeration after purchase is recommended because the suppository melts at around body temperature. Store upright in the outer carton with the tip pointing downward, following the carton markings. Do not use after the expiry date.
Source: Japanese package insert (PDF) · Manufacturer product page.
English summary translated from the manufacturer's Japanese insert; checked September 29, 2026. Read the complete insert before use.
Flady CC1A
メンソレータム フレディCC1A

For recurrent vaginal candidiasis only, after previous diagnosis and treatment by a doctor.
Active ingredient per tablet: Isoconazole nitrate 600 mg. One vaginal tablet in a disposable applicator.
Ages 15 to 59. Do not use under 15 or at 60 and over.
- Do not use if pregnant or possibly pregnant. Consult a pharmacist and read the complete insert before use.
- Single dose only. Do not add further vaginal tablets or suppositories. Do not use during menstruation.
- See a doctor if symptoms do not improve after 3 days or have not disappeared after 6 days.
Directions & precautions
Class 1 OTC medicine. One preloaded, single-use applicator containing one vaginal tablet.
Inactive ingredients: Lactose hydrate, cellulose, carmellose, magnesium stearate.
Directions: Insert one tablet deep into the vagina using the applicator once only, preferably at bedtime. Do not add any other candidiasis vaginal tablets or suppositories. For vaginal use only; do not swallow. If accidentally swallowed, see a doctor immediately.
Wash your hands with soap before use. Open the blister and lift the applicator by its holder, not its plunger. Remove the stopper and keep the same grip throughout insertion. In a relaxed position, gently insert the outer tube diagonally upward until your fingers at the holder reach the vaginal opening, then press the plunger all the way in. Withdraw slowly, discard the applicator and wash your hands with soap. Do not reuse it or use a damaged applicator. See the illustrated application instructions.
Do not use during menstruation. See a doctor if your period starts within 6 days after use. If a tablet comes out undissolved, with its original shape and size, within 6 days, do not insert another yourself; consult a doctor or pharmacist. Small white lumps or paste-like discharge may occur as the medicine leaves the body.
Do not use if:
- You have never had a doctor's diagnosis and treatment for vaginal candidiasis, or are unsure whether this is a recurrence (for example, discharge is not white and cottage-cheese-like, or smells unpleasant).
- You have had a recurrence within 2 months, or two or more within 6 months.
- You have fever, chills, nausea, vomiting, lower abdominal pain, irregular or abnormal bleeding, bloody discharge, vaginal or vulval ulcers, blisters or pain, or painful or difficult urination.
- You have been diagnosed with diabetes, have had an allergic reaction to this medicine or its ingredients, are pregnant or may be pregnant, are under 15, or are 60 or older.
For 6 days after use, do not apply other medicines to the vulva unless they are candidiasis treatments.
Consult a doctor or pharmacist before use if you are receiving medical treatment, breastfeeding, or have had allergic reactions to medicines or other substances.
Possible side effects: Vaginal throbbing pain, swelling, redness, irritation, itching or a feeling of heat. If these occur, immediately consult a doctor or pharmacist with the package insert.
When to see a doctor: If symptoms have not improved after 3 days or have not disappeared after 6 days, seek medical care rather than adding another dose.
For 6 days after use: Avoid sexual intercourse, spermicides and washing inside the vagina. Gently clean the vulva with lukewarm water, not soap. Keep the area dry, change out of wet swimwear, replace panty liners frequently, and wear breathable cotton underwear. Use clean underwear and towels without sharing them. Wipe from front to back and avoid scratching. A partner with symptoms should see a doctor.
Storage: Keep in a cool place away from direct sunlight and out of children's reach. Keep in the original container and do not use after the expiry date.
Source: Japanese package insert (PDF) · Manufacturer product page.
English summary translated from the currently linked Japanese insert; checked September 29, 2026. Read the complete insert before use.
Flady CC1
メンソレータム フレディCC1

For recurrent vaginal candidiasis only, after previous diagnosis and treatment by a doctor.
Active ingredient per tablet: Isoconazole nitrate 600 mg. One vaginal tablet, inserted with a finger.
Ages 15 to 59. Do not use under 15 or at 60 and over.
- Do not use if pregnant or possibly pregnant. Consult a pharmacist and read the complete insert before use.
- Single dose only. Do not add further vaginal tablets or suppositories. Do not use during menstruation.
- See a doctor if symptoms do not improve after 3 days or have not disappeared after 6 days.
Directions & precautions
Class 1 OTC medicine. This is the single-dose tablet inserted with a finger. Flady CC1A is the same dose in a disposable applicator.
Inactive ingredients: Lactose hydrate, cellulose, carmellose, magnesium stearate.
Directions: Insert one tablet deep into the vagina once only, preferably at bedtime. The dose is designed to be enough with one use: the tablet stays in the vagina and works gradually, so do not add any other candidiasis vaginal tablets or suppositories. For vaginal use only; do not swallow. If accidentally swallowed, see a doctor immediately.
Wash your hands with soap and push the tablet out of the blister sheet. In a relaxed position (for example, one foot raised, or crouching), use a fingertip to insert the tablet as deeply as possible into the vagina, then wash your hands with soap. Do not use an applicator with this product. If you want an applicator, use Flady CC1A.
Do not use during menstruation. See a doctor if your period starts within 6 days after use. If the tablet comes out undissolved, with its original shape and size, within 6 days, do not insert another yourself; consult a doctor or pharmacist. Small white lumps or paste-like discharge may occur as the medicine leaves the body.
Do not use if:
- You have never had a doctor's diagnosis and treatment for vaginal candidiasis, or are unsure whether this is a recurrence (for example, discharge is not white and cottage-cheese-like, or smells unpleasant).
- You have had a recurrence within 2 months, or two or more within 6 months.
- You have fever, chills, nausea, vomiting, lower abdominal pain, irregular or abnormal bleeding, bloody discharge, vaginal or vulval ulcers, blisters or pain, or painful or difficult urination.
- You have been diagnosed with diabetes, have had an allergic reaction to this medicine or its ingredients, are pregnant or may be pregnant, are under 15, or are 60 or older.
For 6 days after use, do not apply other medicines to the vulva unless they are candidiasis treatments.
Consult a doctor or pharmacist before use if you are receiving medical treatment, breastfeeding, or have had allergic reactions to medicines or other substances.
Possible side effects: Vaginal throbbing pain, swelling, redness, irritation, itching or a feeling of heat. If these occur, stop using it and consult a doctor or pharmacist with the package insert.
When to see a doctor: If symptoms have not improved after 3 days or have not disappeared after 6 days, seek medical care rather than adding another dose.
For 6 days after use: Avoid sexual intercourse, spermicides and washing inside the vagina. Gently clean the vulva with lukewarm water, not soap. Keep the area dry, change out of wet swimwear, replace panty liners frequently, and wear breathable cotton underwear. Use clean underwear and towels without sharing them. Wipe from front to back and avoid scratching. A partner with symptoms should see a doctor.
Storage: Keep in a cool place away from direct sunlight and out of children's reach. Do not transfer to another container or use after the expiry date.
Source: Japanese package insert (PDF) · Manufacturer product page.
English summary translated from the currently linked Japanese insert; checked October 4, 2026. Read the complete insert before use.
Flady CC (6-day vaginal tablets)
メンソレータム フレディCC 膣錠

For recurrent vaginal candidiasis only, after previous diagnosis and treatment by a doctor.
Active ingredient per tablet: Isoconazole nitrate 100 mg. Pack: 6 vaginal tablets.
Ages 15 to 59. Do not use under 15 or at 60 and over.
- Do not use if pregnant or possibly pregnant. Consult a pharmacist and read the complete insert before use.
- One tablet daily for 6 consecutive days. Insert with a finger, not an applicator. Do not use during menstruation.
- Stop and see a doctor if symptoms do not improve after 3 days or have not disappeared after 6 days.
Directions & precautions
Class 1 OTC medicine. This is the 6-day product, not the single-dose Flady CC1 or CC1A.
Inactive ingredients: Lactose hydrate, cellulose, magnesium stearate.
Directions: Insert one tablet deep into the vagina once daily, preferably at bedtime, for 6 consecutive days. Complete the 6-day course even if symptoms disappear sooner. Stop and see a doctor if symptoms do not improve after 3 days or have not disappeared after 6 days.
Push the tablet through the foil backing of its blister before use. Wash your hands thoroughly with soap. With your knees apart, either squat or lie down, and use a fingertip to insert the tablet as deeply as possible into the vagina. Do not use an applicator. Wash your hands afterward.
For vaginal use only; do not swallow. If accidentally swallowed, see a doctor immediately. Do not use during menstruation. If your period starts during treatment, stop and see a doctor. Small white lumps or paste-like discharge may occur as the medicine leaves the body.
Do not use if:
- You have never had a doctor's diagnosis and treatment for vaginal candidiasis, or are unsure whether this is a recurrence (for example, discharge is not white and cottage-cheese-like, or smells unpleasant).
- You have had a recurrence within 2 months, or two or more within 6 months.
- You have fever, chills, nausea, vomiting, lower abdominal pain, irregular or abnormal bleeding, bloody discharge, vaginal or vulval ulcers, blisters or pain, or painful or difficult urination.
- You have been diagnosed with diabetes, have had an allergic reaction to this medicine or its ingredients, are pregnant or may be pregnant, are under 15, or are 60 or older.
During treatment, do not apply other medicines to the vulva unless they are candidiasis treatments.
Consult a doctor or pharmacist before use if you are receiving medical treatment, breastfeeding, or have had allergic reactions to medicines or other substances.
Possible side effects: Vaginal throbbing pain, swelling, redness, irritation, itching or a feeling of heat. If these occur, stop immediately and consult a doctor or pharmacist with the package insert.
During treatment: Avoid sexual intercourse, spermicides and washing inside the vagina. Gently clean the vulva with lukewarm water rather than soap. Keep the area dry, change out of wet swimwear promptly, replace panty liners frequently, and wear breathable cotton underwear. Use clean underwear and towels without sharing them. Wipe from front to back and avoid scratching. Tell your partner about the infection; if they have symptoms such as genital itching or redness, they should see a doctor promptly.
Storage: Keep in a cool place away from direct sunlight and out of children's reach. Do not transfer to another container or use after the expiry date.
Source: Japanese package insert (PDF) · Manufacturer product page.
English summary translated from the currently linked Japanese insert; checked September 29, 2026. Read the complete insert before use.
Empecid L (vaginal tablets)
エンペシドL

For recurrent vaginal candidiasis only, after previous diagnosis and treatment by a doctor.
Active ingredient per tablet: Clotrimazole 100 mg. Pack: 6 vaginal tablets.
Ages 15 to 59. Do not use under 15 or at 60 and over.
- Do not use if pregnant or possibly pregnant. Consult a pharmacist and read the complete insert before use.
- One tablet daily for 6 consecutive days. Insert with a finger, not an applicator. Do not use during menstruation.
- See a doctor if symptoms do not improve after 3 days or have not disappeared after 6 days.
Directions & precautions
Class 1 OTC medicine. These are vaginal tablets, not Empecid L Cream.
Inactive ingredients: Lactose, corn starch, pregelatinized starch, adipic acid, sodium bicarbonate, magnesium stearate, stearic acid, polysorbate 80, anhydrous silica.
Directions: Insert one tablet deep into the vagina once daily, preferably at bedtime, for 6 consecutive days. Complete the 6-day course even if symptoms disappear sooner. Follow the stated dose and schedule.
Before use, bathe or clean the affected area with lukewarm water. Wash your hands with soap, then use a fingertip to insert the tablet as deeply as possible into the vagina. Wash your hands with soap afterward. Do not use an applicator.
Use only inside the vagina, not on other parts of the body. Do not swallow; if accidentally swallowed, see a doctor immediately. Do not use during menstruation. If your period starts during treatment, stop and see a doctor to check whether the infection has cleared.
Do not use if:
- This may be your first episode, you have not previously had a doctor's diagnosis and treatment, or you are unsure whether this is a recurrence.
- You have had an allergic reaction to this medicine or its ingredients, are pregnant or may be pregnant, are under 15, or are 60 or older.
- You have fever, chills, lower abdominal pain, back or shoulder pain, colored or blood-stained discharge, fishy-smelling discharge, missed periods, irregular or abnormal vaginal bleeding, or vaginal or vulval ulcers, swelling or sores.
- You have been diagnosed with diabetes.
- Episodes recur every 1 to 2 months, or you have had two or more episodes within 6 months.
During treatment, do not apply other medicines to the vulva unless they are candidiasis treatments.
Consult a doctor or pharmacist before use if you are receiving medical treatment, have had allergic reactions to medicines or other substances, or are breastfeeding.
Possible side effects: Vaginal heat, irritation, itching, redness or pain, and skin rash. If these appear, persist or become stronger after use, stop immediately and consult a doctor or pharmacist with the package insert.
When to see a doctor: If symptoms do not improve after 3 days of use or have not disappeared after 6 days, see a doctor and take the package insert with you.
Storage: Keep in a cool, dry place away from direct sunlight and out of children's reach. Do not transfer to another container or use after the expiry date.
Source: Japanese package insert (PDF) · Manufacturer product page.
English summary translated from the Japanese insert, revised January 2017 and currently linked by the manufacturer; checked September 29, 2026. Read the complete insert before use.
Creams
Meditreat Cream
メディトリートクリーム

For vulval itching with a rash caused by recurrent vaginal candidiasis, after previous diagnosis and treatment by a doctor. Not for unrelated itching or irritation.
Active ingredient per 1 g: Miconazole nitrate 10 mg (1%). Pack: 10 g cream.
Ages 15 to 59. Do not use under 15 or at 60 and over.
- For the vulva only, not inside the vagina. If vaginal symptoms such as discharge or a feeling of heat are present, a vaginal medicine must also be used.
- Do not use if pregnant or possibly pregnant, or if taking anticoagulants such as warfarin. Consult a pharmacist and read the complete insert before use.
- See a doctor if symptoms do not improve after 3 days or have not disappeared after 6 days.
Directions & precautions
Class 1 OTC medicine. This cream treats external symptoms caused by Candida; it does not treat infection inside the vagina.
Directions: Apply an appropriate amount to the affected vulval area 2 to 3 times daily. If symptoms are external only, the cream can be used, although combined use with a vaginal medicine is preferred. If vaginal symptoms such as discharge or a feeling of heat are present, combined use with a vaginal medicine is required.
Before use, bathe or clean the affected area with lukewarm water. Wash your hands well before and after application. To open the tube, turn the cap upside down and firmly press its pointed end into the tube seal. Follow the stated dose and schedule.
Use only on the vulva. Avoid contact with the eyes; if cream gets into your eyes, immediately rinse with water or lukewarm water and see an ophthalmologist. Avoid use during menstruation. If your period starts during treatment, stop and see a doctor to check whether the infection has cleared.
Do not use if:
- This may be your first episode, you have not previously had a doctor's diagnosis and treatment, or you are unsure whether this is a recurrence.
- You have had an allergic reaction to this medicine or its ingredients, are pregnant or may be pregnant, are under 15, or are 60 or older.
- You have fever, chills, lower abdominal pain, back or shoulder pain, colored or blood-stained discharge, fishy-smelling discharge, missed periods, irregular or abnormal vaginal bleeding, or vaginal or vulval ulcers, swelling or sores.
- You have been diagnosed with diabetes or take anticoagulants such as warfarin.
- Episodes recur every 1 to 2 months, or you have had two or more episodes within 6 months.
Consult a doctor or pharmacist before use if you are receiving medical treatment, have had allergic reactions to medicines or other substances, or are breastfeeding.
Possible side effects: Vulval itching, rash or redness, dermatitis, a feeling of heat, skin erosion, irritation, small blisters, swelling, dryness or cracking, and peeling. If these persist or worsen, stop using the cream and consult a doctor or pharmacist with the package insert.
When to see a doctor: If symptoms do not improve after 3 days or have not disappeared after 6 days, seek medical care. This is especially important when using the cream alone; do not continue self-treatment without a doctor's assessment.
Latex precautions: Avoid contact with latex contraceptives such as condoms or diaphragms, as the cream may cause them to deteriorate or break.
Inactive ingredients: Polyoxyethylene cetyl ether, self-emulsifying glyceryl monostearate, paraben, isopropyl myristate, liquid paraffin, cetyl alcohol.
Storage: Keep tightly capped in a cool place away from direct sunlight and out of children's reach. Do not transfer to another container or use after the expiry date. Use as soon as possible after opening, even if still within the expiry date.
Source: Japanese package insert (PDF) · Manufacturer product page.
English summary translated from the Japanese insert, revised February 2017 and currently linked by the manufacturer; checked September 29, 2026. Read the complete insert before use.
Flady CC Cream
メンソレータム フレディCCクリーム

For vulval itching with a rash caused by recurrent vaginal candidiasis, after previous diagnosis and treatment by a doctor. Not for unrelated itching or irritation.
Active ingredient: Isoconazole nitrate 1%. Pack: 10 g cream.
Ages 15 to 59. Do not use under 15 or at 60 and over.
- For the vulva only, not inside the vagina. If vaginal symptoms such as discharge or a feeling of heat are present, a vaginal medicine must also be used.
- Do not use if pregnant or possibly pregnant. Consult a pharmacist and read the complete insert before use.
- Stop and see a doctor if symptoms do not improve after 3 days or have not disappeared after 6 days.
Directions & precautions
Class 1 OTC medicine. This cream treats external symptoms caused by Candida; it does not treat infection inside the vagina.
Directions: Apply an appropriate amount to the affected vulval area 2 to 3 times daily. If symptoms are external only, the cream can be used, although combined use with a vaginal medicine is preferred. If vaginal symptoms such as discharge or a feeling of heat are present, combined use with a vaginal medicine is required.
Wash your hands thoroughly with soap before and after use. Use only on the vulva, not on other areas such as the nails, scalp or eyes. If cream gets into your eyes, immediately rinse with water or lukewarm water and see an ophthalmologist.
Do not use during menstruation. If your period starts during treatment, stop and see a doctor to check whether the infection has cleared.
Do not use if:
- You have never had a doctor's diagnosis and treatment for vaginal candidiasis, or are unsure whether this is a recurrence.
- You have had a recurrence within 2 months, or two or more within 6 months.
- You have fever, chills, nausea, vomiting, lower abdominal pain, irregular or abnormal bleeding, bloody discharge, vaginal or vulval ulcers, blisters or pain, painful or difficult urination, or severely eroded skin.
- You have been diagnosed with diabetes, have had an allergic reaction to this medicine or its ingredients, are pregnant or may be pregnant, are under 15, or are 60 or older.
Consult a doctor or pharmacist before use if you are receiving medical treatment, breastfeeding, or have had allergic reactions to medicines or other substances.
Possible side effects: Skin irritation, redness, itching, dermatitis or throbbing pain. If these occur after use, stop immediately and consult a doctor or pharmacist with the package insert.
When to see a doctor: Stop and seek medical care if symptoms do not improve after 3 days or have not disappeared after 6 days. In particular, if the cream alone is not effective, do not continue treating yourself without a doctor's assessment.
Latex precautions: Avoid contact with latex contraceptives such as condoms, as the cream may cause them to deteriorate or break.
During treatment: Avoid sexual intercourse and spermicides. Gently clean the vulva with warm water rather than soap. Keep the area dry, change out of wet swimwear promptly, replace panty liners frequently, and wear breathable cotton underwear. Use clean underwear and towels daily without sharing towels. Wipe from front to back and avoid scratching. Tell your partner about the infection; if they have genital itching, a rash or other symptoms, they should see a doctor promptly.
Inactive ingredients: Polysorbate 60, sorbitan stearate, cetostearyl alcohol, liquid paraffin, petrolatum.
Storage: Keep tightly capped in a cool place away from direct sunlight and out of children's reach. Do not transfer to another container or use after the expiry date. Use as soon as possible after opening, even if still within the expiry date.
Source: Japanese package insert (PDF) · Manufacturer product page.
English summary translated from the currently linked Japanese insert; checked September 29, 2026. Read the complete insert before use.
Empecid L Cream
エンペシドLクリーム

For vulval itching with a rash caused by recurrent vaginal candidiasis, after previous diagnosis and treatment by a doctor. Not for unrelated itching or irritation.
Active ingredient: Clotrimazole 1%. Pack: 10 g cream.
Ages 15 to 59. Do not use under 15 or at 60 and over.
- For the vulva only, not inside the vagina. If vaginal symptoms such as discharge or a feeling of heat are present, a vaginal medicine must also be used.
- Do not use if pregnant or possibly pregnant. Consult a pharmacist and read the complete insert before use.
- Stop and see a doctor if symptoms do not improve after 3 days or have not disappeared after 6 days.
Directions & precautions
Class 1 OTC medicine. This cream treats external symptoms caused by Candida; it does not treat infection inside the vagina.
Directions: Apply an appropriate amount to the affected vulval area 2 to 3 times daily. If symptoms are external only, the cream can be used, although combined use with a vaginal medicine is preferred. If vaginal symptoms such as discharge or a feeling of heat are present, combined use with a vaginal medicine is required.
Wash your hands thoroughly with soap before and after use. Use only on the vulva. Be careful not to get it in your eyes; if it does, rinse immediately with water or lukewarm water and see an eye doctor at once.
Do not use during menstruation. If your period starts during treatment, stop using it and see a doctor to check whether the infection has cleared.
Do not use if:
- This may be your first episode, you have not previously had a doctor's diagnosis and treatment, or you are unsure whether this is a recurrence.
- You have had an allergic reaction to this medicine or its ingredients, are pregnant or may be pregnant, are under 15, or are 60 or older.
- You have fever, chills, lower abdominal pain, back or shoulder pain, colored or blood-stained discharge, fishy-smelling discharge, missed periods, irregular or abnormal vaginal bleeding, or vaginal or vulval ulcers, swelling or sores.
- You have been diagnosed with diabetes.
- Episodes recur every 1 to 2 months, or you have had two or more episodes within 6 months.
Consult a doctor or pharmacist before use if you are receiving medical treatment, have had allergic reactions to medicines or other substances, or are breastfeeding.
Possible side effects (skin around the vulva): Irritation, dermatitis, redness, red rash, skin sores, small raised rash, heat, itching or pain. If these appear, persist or become stronger after use, stop immediately and consult a doctor or pharmacist with the package insert.
When to see a doctor: If symptoms do not improve after 3 days of use or have not disappeared after 6 days, see a doctor and take the package insert with you. If the cream alone is not effective, do not keep treating yourself; see a doctor, as symptoms may be more serious or have another cause.
Latex precautions: Avoid contact with latex contraceptives such as condoms and pessaries, as the cream may damage or break them.
Inactive ingredients: Sorbitan stearate, polysorbate 60, cetyl myristate, cetostearyl alcohol, octyldodecanol, benzyl alcohol.
Storage: Keep tightly capped in a cool place with low humidity, away from direct sunlight and out of children's reach. Do not transfer to another container or use after the expiry date. Even within the expiry date, use it as soon as possible after opening.
Source: Japanese package insert (PDF) · Manufacturer product page.
English summary translated from the currently linked Japanese insert; checked October 4, 2026. Read the complete insert before use.